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Measurement of CSF core Alzheimer disease biomarkers for routine clinical diagnosis: do fresh vs frozen samples differ?

BACKGROUND: Cerebrospinal fluid (CSF) amyloid-beta (Aβ) 42/40 ratio, threonine-181-phosphorylated-tau (p-tau), and total-tau (t-tau) represent core biomarkers of Alzheimer disease (AD). The recent availability of automated platforms has represented a significant achievement for reducing the pre-anal...

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Bibliographische Detailangaben
Veröffentlicht in:Alzheimers Res Ther
Hauptverfasser: Bellomo, Giovanni, Cataldi, Samuela, Paciotti, Silvia, Paolini Paoletti, Federico, Chiasserini, Davide, Parnetti, Lucilla
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526419/
https://ncbi.nlm.nih.gov/pubmed/32993776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00689-0
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