bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice

Intraplaque angiogenesis increases the chance of unstable atherosclerotic plaque rupture and thrombus formation leading to myocardial infarction. Basic Fibroblast Growth Factor (bFGF) plays a key role in angiogenesis and inflammation and is involved in the pathogenesis of atherosclerosis. Therefore,...

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Publicado no:Sci Rep
Main Authors: Parma, Laura, Peters, Hendrika A. B., Sluiter, Thijs J., Simons, Karin H., Lazzari, Paolo, de Vries, Margreet R., Quax, Paul H. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525538/
https://ncbi.nlm.nih.gov/pubmed/32994514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72992-7
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