RegX3 Activates whiB3 Under Acid Stress and Subverts Lysosomal Trafficking of Mycobacterium tuberculosis in a WhiB3-Dependent Manner

Two-component systems (TCSs) are central to the ability of Mycobacterium tuberculosis to respond to stress. One such paired TCS is SenX3-RegX3, which responds to phosphate starvation. Here we show that RegX3 is required for M. tuberculosis to withstand low pH, one of the challenges encountered by th...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: Mahatha, Amar Chandra, Mal, Soumya, Majumder, Debayan, Saha, Sudipto, Ghosh, Abhirupa, Basu, Joyoti, Kundu, Manikuntala
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525159/
https://ncbi.nlm.nih.gov/pubmed/33042081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.572433
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