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Deletion of the adenosine A(2A) receptor increases the survival rate in a mice model of polymicrobial sepsis

We aim to investigate the role of A(2A) receptor in peritonitis-related sepsis by injection of a fecal solution (FS) as a model of polymicrobial infection. C57/black J6 wild-type (WT) and A(2A)-deficient mice (A(2A)KO) were exposed to sepsis induced by intraperitoneal injection of a FS (FS-induced p...

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Detalles Bibliográficos
Publicado en:Purinergic Signal
Main Authors: Meriño, Miguel, Martín, Sebastián San, Sandaña, Pedro, Herlitz, Kurt, Aguayo, Claudio, Godoy, Alejandro, Torres-Vergara, Pablo, Gonzalez, Marcelo, Troncoso, Felipe, Acurio, Jesenia, Escudero, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524982/
https://ncbi.nlm.nih.gov/pubmed/32808144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09719-w
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