Involvement of adenosine A(1) and A(2A) receptors on guanosine-mediated anti-tremor effects in reserpinized mice

Parkinson’s disease (PD) signs and symptoms regularly include tremor. Interestingly, the nucleoside guanosine (GUO) has already proven to be effective in reducing reserpine-induced tremulous jaw movements (TJMs) in rodent models, thus becoming a promising antiparkinsonian drug. Here, we aimed at rev...

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Enregistré dans:
Détails bibliographiques
Publié dans:Purinergic Signal
Auteurs principaux: Massari, C. M., Constantino, L. C., Marques, N. F., Binder, L. B., Valle-León, M., López-Cano, M., Fernández-Dueñas, V., Ciruela, F., Tasca, C. I.
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2020
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524909/
https://ncbi.nlm.nih.gov/pubmed/32725400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09716-z
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