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HIFs, angiogenesis, and metabolism: elusive enemies in breast cancer

Hypoxia-inducible factors (HIFs) and the HIF-dependent cancer hallmarks angiogenesis and metabolic rewiring are well-established drivers of breast cancer aggressiveness, therapy resistance, and poor prognosis. Targeting of HIF and its downstream targets in angiogenesis and metabolism has been unsucc...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: de Heer, Ellen C., Jalving, Mathilde, Harris, Adrian L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524491/
https://ncbi.nlm.nih.gov/pubmed/32870818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137552
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