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Glioma escape signature and clonal development under immune pressure

Immunotherapeutic strategies are increasingly important in neuro-oncology, and the elucidation of escape mechanisms that lead to treatment resistance is crucial. We investigated the impact of immune pressure on the clonal dynamics and immune escape signature by comparing glioma growth in immunocompe...

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Опубликовано в: :J Clin Invest
Главные авторы: Maire, Cecile L., Mohme, Malte, Bockmayr, Michael, Fita, Krystian D., Riecken, Kristoffer, Börnigen, Daniela, Alawi, Malik, Failla, Antonio, Kolbe, Katharina, Zapf, Svenja, Holz, Mareike, Neumann, Katrin, Dührsen, Lasse, Lange, Tobias, Fehse, Boris, Westphal, Manfred, Lamszus, Katrin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524465/
https://ncbi.nlm.nih.gov/pubmed/32603315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI138760
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