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Knockdown of circPRKCA Restrained Cell Growth, Migration, and Invasion of NSCLC Cells Both in vitro and in vivo via Regulating miR-330-5p/PDK1/AKT Pathway

BACKGROUND: Protein kinase Cα (PRKCA) is an oncogene in multiple cancers including non-small-cell lung cancer (NSCLC) and can be transcribed into a number of circular PRKCAs (circPRKCAs). Here, we aimed to elaborate the role and mechanism of circPRKCA_024 (circPRKCA) in malignant progression of NSCL...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Bai, Lanxiang, Peng, Xiaonu, Sun, Ruimei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524182/
https://ncbi.nlm.nih.gov/pubmed/33061606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S258370
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