Efficacy and safety of short-term use of a pelubiprofen CR and aceclofenac in patients with symptomatic knee osteoarthritis: A double-blinded, randomized, multicenter, active drug comparative, parallel-group, phase IV, non-inferiority clinical trial

INTRODUCTION: At present, information about clinical efficacy and adverse events of controlled release (CR) form of pelubiprofen, a prodrug of 2-arylopropionic acid with relatively selective effects on cyclooxygenase-2 activity, remains scarce. In this study, we sought to determine non-inferiority o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shin, Joung Youp, Chang, Moon Jong, Kim, Myung Ku, Kang, Seung-Baik, Kim, Kang-Il, Park, Hee Gon, Lee, Sahnghoon, Kim, Sung-Hwan, Han, Seung-Beom, Lee, Han Jun, Moon, Young-Wan, Yoo, Jae-Doo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523996/
https://ncbi.nlm.nih.gov/pubmed/32991606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238024
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