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DNA-Peptide Amphiphile Nanofibers Enhance Aptamer Function

The single stranded DNA oligonucleotides known as aptamers have the capacity to bind proteins and other molecules and offer great therapeutic potential. Further work is required to optimize their function and to diminish their susceptibility to nuclease degradation. We report here on the synthesis a...

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Pubblicato in:ACS Appl Bio Mater
Autori principali: Serrano, Christopher M., Freeman, Ronit, Godbe, Jacqueline, Lewis, Jacob A., Stupp, Samuel I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523912/
https://ncbi.nlm.nih.gov/pubmed/32999996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsabm.9b00310
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