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BAGSE: a Bayesian hierarchical model approach for gene set enrichment analysis

MOTIVATION: Gene set enrichment analysis has been shown to be effective in identifying relevant biological pathways underlying complex diseases. Existing approaches lack the ability to quantify the enrichment levels accurately, hence preventing the enrichment information to be further utilized in bo...

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Vydáno v:Bioinformatics
Hlavní autoři: Hukku, Abhay, Quick, Corbin, Luca, Francesca, Pique-Regi, Roger, Wen, Xiaoquan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523653/
https://ncbi.nlm.nih.gov/pubmed/31702789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz831
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