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Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) depletion regulates spermatogenic cell apoptosis and is correlated with hypospermatogenesis

Phosphoribosyl-pyrophosphate synthetase 2 (PRPS2) is a rate-limiting enzyme and plays an important role in purine and pyrimidine nucleotide synthesis. Recent studies report that PRPS2 is involved in male infertility. However, the role of PRPS2 in hypospermatogenesis is unknown. In this study, the re...

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Detalhes bibliográficos
Publicado no:Asian J Androl
Main Authors: Lei, Bin, Xie, Li-Xia, Zhang, Shou-Bo, Wan, Bo, Zhong, Li-Ren, Zhou, Xu-Ming, Mao, Xiang-Ming, Shu, Fang-Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523602/
https://ncbi.nlm.nih.gov/pubmed/31736475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/aja.aja_122_19
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