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pH-responsive and hyaluronic acid-functionalized metal–organic frameworks for therapy of osteoarthritis
Drug therapy of osteoarthritis (OA) is limited by the short retention and lacking of stimulus-responsiveness after intra-articular (IA) injection. The weak acid microenvironment in joint provides a potential trigger for controlled drug release systems in the treatment of OA. Herein, we developed an...
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| Publicado no: | J Nanobiotechnology |
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| Principais autores: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7523381/ https://ncbi.nlm.nih.gov/pubmed/32993662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00694-3 |
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