SARS-CoV-2 antibody signatures robustly predict diverse antiviral functions relevant for convalescent plasma therapy

Convalescent plasma has emerged as a promising COVID-19 treatment. However, the humoral factors that contribute to efficacy are poorly understood. This study functionally and phenotypically profiled plasma from eligible convalescent donors. In addition to viral neutralization, convalescent plasma co...

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Publicado en:medRxiv
Main Authors: Natarajan, Harini, Crowley, Andrew R., Butler, Savannah E., Xu, Shiwei, Weiner, Joshua A., Bloch, Evan M., Littlefield, Kirsten, Wieland-Alter, Wendy, Connor, Ruth I., Wright, Peter F., Benner, Sarah E., Bonny, Tania S., Laeyendecker, Oliver, Sullivan, David, Shoham, Shmuel, Quinn, Thomas C., Larman, H. Benjamin, Casadevall, Arturo, Pekosz, Andrew, Redd, Andrew D., Tobian, Aaron A.R., Ackerman, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523138/
https://ncbi.nlm.nih.gov/pubmed/32995801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.16.20196154
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