Differential Associations of Apolipoprotein E ε4 Genotype With Attentional Abilities Across the Life Span of Individuals With Down Syndrome

IMPORTANCE: Risk of Alzheimer disease (AD) is particularly high for individuals with Down syndrome (DS). The ε4 allele of the apolipoprotein E gene (APOE ε4) is associated with an additional risk for AD. In typical development, there is evidence that the APOE ε4 genotype is associated with an early...

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Dettagli Bibliografici
Pubblicato in:JAMA Netw Open
Autori principali: D’Souza, Hana, Mason, Luke, Mok, Kin Y., Startin, Carla M., Hamburg, Sarah, Hithersay, Rosalyn, Baksh, R. Asaad, Hardy, John, Strydom, Andre, Thomas, Michael S. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2020
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522696/
https://ncbi.nlm.nih.gov/pubmed/32986108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2020.18221
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