Ubc9 Attenuates Myocardial Ischemic Injury Through Accelerating Autophagic Flux

AIMS: SUMOylation is a post-translational modification that plays a crucial role in the cellular stress response. We aimed to demonstrate whether and how the SUMO E2 conjugation enzyme Ubc9 affects acute myocardial ischemic (MI) injury. METHODS AND RESULTS: Adenovirus expressing Ubc9 was administrat...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xiao, Qing, Chen, Xiu-Hui, Jiang, Ru-Chao, Chen, Sheng-Ying, Chen, Kai-Feng, Zhu, Xiang, Zhang, Xiao-ling, Huang, Jun-jun, Qin, Yuan, Zhang, Gui-Ping, Yi, Quan, Luo, Jian-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522513/
https://ncbi.nlm.nih.gov/pubmed/33041800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.561306
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