Evaluation of therapeutic efficacy of (211)At-labeled farletuzumab in an intraperitoneal mouse model of disseminated ovarian cancer

INTRODUCTION: Antibodies labeled with alpha-emitter astatine-211 have previously shown effective in intraperitoneal (i.p.) treatments of ovarian cancer. In the present work we explore the use of investigational farletuzumab, aimed at the folate receptor alpha. The aim was to evaluate the biodistribu...

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Enregistré dans:
Détails bibliographiques
Publié dans:Transl Oncol
Auteurs principaux: Palm, Stig, Bäck, Tom, Aneheim, Emma, Hallqvist, Andreas, Hultborn, Ragnar, Jacobsson, Lars, Jensen, Holger, Lindegren, Sture, Albertsson, Per
Format: Artigo
Langue:Inglês
Publié: Neoplasia Press 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522120/
https://ncbi.nlm.nih.gov/pubmed/32987283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100873
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