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Correlating nuclear morphology and external force with combined atomic force microscopy and light sheet imaging separates roles of chromatin and lamin A/C in nuclear mechanics

Nuclei are often under external stress, be it during migration through tight constrictions or compressive pressure by the actin cap, and the mechanical properties of nuclei govern their subsequent deformations. Both altered mechanical properties of nuclei and abnormal nuclear morphologies are hallma...

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Bibliografische gegevens
Gepubliceerd in:Mol Biol Cell
Hoofdauteurs: Hobson, Chad M., Kern, Megan, O’Brien, E. Timothy, Stephens, Andrew D., Falvo, Michael R., Superfine, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Cell Biology 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521857/
https://ncbi.nlm.nih.gov/pubmed/32267206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-01-0073
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