Restoration of functional sperm production in irradiated pubertal rhesus monkeys by spermatogonial stem cell transplantation

BACKGROUND: In male pre-pubertal cancer patients, radiation and chemotherapy impact future fertility by eradication of spermatogonial stem cells (SSCs). In macaques, spermatogenesis could be regenerated by intratesticular transplantation of SSCs, but only a small percentage of spermatozoa produced w...

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Publicado en:Andrology
Autores principales: Shetty, Gunapala, Mitchell, Jennifer M., Meyer, Jennifer M., Wu, Zhuang, Lam, Truong N.A., Phan, Thien T., Zhang, Jie, Hill, Lorraine, Tailor, Ramesh C., Peters, Karen A., Penedo, Maria C., Hanna, Carol, Orwig, Kyle E., Meistrich, Marvin L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521830/
https://ncbi.nlm.nih.gov/pubmed/32351003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/andr.12807
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