Restoration of functional sperm production in irradiated pubertal rhesus monkeys by spermatogonial stem cell transplantation

BACKGROUND: In male pre-pubertal cancer patients, radiation and chemotherapy impact future fertility by eradication of spermatogonial stem cells (SSCs). In macaques, spermatogenesis could be regenerated by intratesticular transplantation of SSCs, but only a small percentage of spermatozoa produced w...

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Detalhes bibliográficos
Publicado no:Andrology
Main Authors: Shetty, Gunapala, Mitchell, Jennifer M., Meyer, Jennifer M., Wu, Zhuang, Lam, Truong N.A., Phan, Thien T., Zhang, Jie, Hill, Lorraine, Tailor, Ramesh C., Peters, Karen A., Penedo, Maria C., Hanna, Carol, Orwig, Kyle E., Meistrich, Marvin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521830/
https://ncbi.nlm.nih.gov/pubmed/32351003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/andr.12807
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