Mining a human transcriptome database for chemical modulators of NRF2

Nuclear factor erythroid-2 related factor 2 (NRF2) encoded by the NFE2L2 gene is a transcription factor critical for protecting cells from chemically-induced oxidative stress. We developed computational procedures to identify chemical modulators of NRF2 in a large database of human microarray data....

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Rooney, John P., Chorley, Brian, Hiemstra, Steven, Wink, Steven, Wang, Xuting, Bell, Douglas A., van de Water, Bob, Corton, J. Christopher
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521735/
https://ncbi.nlm.nih.gov/pubmed/32986742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239367
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