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High-density lipoproteins are a potential therapeutic target for age-related macular degeneration

Strong evidence suggests that dysregulated lipid metabolism involving dysfunction of the retinal pigmented epithelium (RPE) underlies the pathogenesis of age-related macular degeneration (AMD), the leading cause of irreversible blindness in the elderly. A hallmark of AMD is the overproduction of lip...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kelly, Una L., Grigsby, Daniel, Cady, Martha A., Landowski, Michael, Skiba, Nikolai P., Liu, Jian, Remaley, Alan T., Klingeborn, Mikael, Bowes Rickman, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521644/
https://ncbi.nlm.nih.gov/pubmed/32737203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.012305
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