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The mechano-sensitive response of β1 integrin promotes SRC-positive late endosome recycling and activation of Yes-associated protein

Yes-associated protein (YAP) signaling has emerged as a crucial pathway in several normal and pathological processes. Although the main upstream effectors that regulate its activity have been extensively studied, the role of the endosomal system has been far less characterized. Here, we identified t...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Block, Marc R., Brunner, Molly, Ziegelmeyer, Théo, Lallemand, Dominique, Pezet, Mylène, Chevalier, Genevieve, Rondé, Philippe, Gauthier-Rouviere, Cécile, Wehrle-Haller, Bernhard, Bouvard, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521633/
https://ncbi.nlm.nih.gov/pubmed/32690605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013503
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