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Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats

Postoperative cognitive dysfunction (POCD) is frequently observed in elderly patients following anesthesia, but its pathophysiological mechanisms have not been fully elucidated. Sevoflurane was reported to repress autophagy in aged rat neurons; however, the role of mitophagy, which is crucial for th...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Chen, Yeru, Zhang, Piao, Lin, Xianyi, Zhang, Huan, Miao, Jiamin, Zhou, Youfa, Chen, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521530/
https://ncbi.nlm.nih.gov/pubmed/32903215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103673
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