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Empagliflozin in Heart Failure: Diuretic and Cardio-renal Effects

BACKGROUND: Sodium-glucose cotransporter-2 inhibitors (SGLT-2i’s) improve heart failure (HF) related outcomes. The mechanisms underlying these benefits are not well understood, but diuretic properties may contribute. Traditional diuretics, such as furosemide, induce substantial neurohormonal activat...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Griffin, Matthew, Rao, Veena S., Ivey-Miranda, Juan, Fleming, James, Mahoney, Devin, Maulion, Christopher, Suda, Nisha, Siwakoti, Krishmita, Ahmad, Tariq, Jacoby, Daniel, Riello, Ralph, Bellumkonda, Lavanya, Cox, Zachary, Collins, Sean, Jeon, Sangchoon, Turner, Jeffrey M., Wilson, F. Perry, Butler, Javed, Inzucchi, Silvio E., Testani, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521417/
https://ncbi.nlm.nih.gov/pubmed/32410463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.120.045691
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