CD8(+) T‐cell senescence and skewed lymphocyte subsets in young Dyskeratosis Congenita patients with PARN and DKC1 mutations

BACKGROUND: Dyskeratosis congenita (DC) is a syndrome resulting from defective telomere maintenance. Immunodeficiency associated with DC can cause significant morbidity and lead to premature mortality, but the immunological characteristics and molecular hallmark of DC patients, especially young pati...

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Bibliografski detalji
Izdano u:J Clin Lab Anal
Glavni autori: Zeng, Ting, Lv, Ge, Chen, Xuemei, Yang, Lu, Zhou, Lina, Dou, Ying, Tang, Xuemei, Yang, Jun, An, Yunfei, Zhao, Xiaodong
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
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Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521304/
https://ncbi.nlm.nih.gov/pubmed/32452087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23375
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