Inhibition of αvβ3 integrin impairs adhesion and uptake of tumor-derived small extracellular vesicles

BACKGROUND: Extracellular vesicles (EVs) are lipid-bound particles that are naturally released from cells and mediate cell-cell communication. Integrin adhesion receptors are enriched in small EVs (SEVs) and SEV-carried integrins have been shown to promote cancer cell migration and to mediate organ-...

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Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Altei, Wanessa F., Pachane, Bianca C., dos Santos, Patty K., Ribeiro, Lígia N. M., Sung, Bong Hwan, Weaver, Alissa M., Selistre-de-Araújo, Heloisa S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520983/
https://ncbi.nlm.nih.gov/pubmed/32988382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00630-w
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