Time-dependent LPS exposure commands MSC immunoplasticity through TLR4 activation leading to opposite therapeutic outcome in EAE

BACKGROUND: Mesenchymal stem cells (MSCs) have been recognized for their regenerative and anti-inflammatory capacity which makes them very attractive to cell therapy, especially those ones to treat inflammatory and autoimmune disease. Two different immune-phenotypes have been described for MSCs depe...

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Bibliografski detalji
Izdano u:Stem Cell Res Ther
Glavni autori: Kurte, Mónica, Vega-Letter, Ana María, Luz-Crawford, Patricia, Djouad, Farida, Noël, Danièle, Khoury, Maroun, Carrión, Flavio
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520958/
https://ncbi.nlm.nih.gov/pubmed/32988406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01840-2
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