Peritumoral activated hepatic stellate cells are associated with hepatic recurrence for resectable colorectal adenocarcinoma liver metastasis following resection

The formation of the pre-metastatic niche (PMN), which precedes the establishment of tumor lesions, plays a critical role in cancer recurrence and metastasis. Hepatic stellate cells (HSCs), a critical liver stromal cell component, can be induced to facilitate metastasis by modeling liver PMN formati...

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Published in:Oncol Lett
Main Authors: Deng, Li, Li, Taiyuan, Liao, Yuanyuan, Liu, Shuang, Xie, Zhen, Huang, Zhixiang, Dai, Hua, Li, Jianfeng, Lei, Xiong
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520724/
https://ncbi.nlm.nih.gov/pubmed/33014165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12150
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