Predicted Efficacy of Once-Daily Extended-Release Oxcarbazepine (Oxtellar XR(®)) Monotherapy in Adults and Children with Partial-Onset Seizures: Exposure-Response Modeling and Simulation

PURPOSE: We conducted exposure-response modeling and simulations to compare the predicted efficacy of extended-release oxcarbazepine (OXC-XR), an oral once-daily (qd) antiepileptic drug, with that of immediate-release (IR) OXC twice-daily (bid) when the agents are used as monotherapy or adjunctive t...

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Detaylı Bibliyografya
Yayımlandı:Clin Pharmacol
Asıl Yazarlar: Faison, Shamia, Gomeni, Roberto, Mendes, Shannon, O’Neal, Welton, Schwabe, Stefan, Nasser, Azmi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520464/
https://ncbi.nlm.nih.gov/pubmed/33061671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S256972
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