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Apatinib attenuates phenotypic switching of arterial smooth muscle cells in vascular remodelling by targeting the PDGF Receptor‐β

Apatinib (YN968D1) is a small‐molecule tyrosine kinase inhibitor(TKI)which can inhibit the activity of vascular endothelial growth factor receptor‐2 (VEGFR‐2). It has been reported that apatinib has anti‐tumour effect of inhibiting proliferation and inducing apoptosis of a variety of solid tumour ce...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Shao, Wenchao, Li, Xiaoguang, Peng, Jiangtong, Fan, Siyuan, Liang, Minglu, Huang, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520274/
https://ncbi.nlm.nih.gov/pubmed/32697395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15623
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