Metformin may adversely affect orthostatic blood pressure recovery in patients with type 2 diabetes: substudy from the placebo-controlled Copenhagen Insulin and Metformin Therapy (CIMT) trial

BACKGROUND: Metformin has been shown to have both neuroprotective and neurodegenerative effects. The aim of this study was to investigate the effect of metformin in combination with insulin on cardiovascular autonomic neuropathy (CAN) and distal peripheral neuropathy (DPN) in individuals with type 2...

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Vydáno v:Cardiovasc Diabetol
Hlavní autoři: Hansen, Christian Stevns, Lundby-Christiansen, Louise, Tarnow, Lise, Gluud, Christian, Hedetoft, Christoffer, Thorsteinsson, Birger, Hemmingsen, Bianca, Wiinberg, Niels, Sneppen, Simone B., Lund, Søren S., Krarup, Thure, Madsbad, Sten, Almdal, Thomas, Carstensen, Bendix, Jørgensen, Marit E.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520024/
https://ncbi.nlm.nih.gov/pubmed/32979921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-020-01131-3
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