The miR-361-3p increases enzalutamide (Enz) sensitivity via targeting the ARv7 and MKNK2 to better suppress the Enz-resistant prostate cancer

The androgen receptor splicing variant 7 (ARv7) that lacks the ligand-binding domain is increasingly considered as a key player leading to enzalutamide (Enz) resistance in patients with prostate cancer (PCa). However, the detailed mechanisms of how ARv7 expression is regulated and whether it also ne...

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Опубликовано в: :Cell Death Dis
Главные авторы: Liu, Bianjiang, Sun, Yin, Tang, Min, Liang, Chao, Huang, Chi-Ping, Niu, Yuanjie, Wang, Zengjun, Chang, Chawnshang
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519644/
https://ncbi.nlm.nih.gov/pubmed/32978369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02932-w
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