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Mycobacterium tuberculosis progresses through two phases of latent infection in humans

Little is known about the physiology of latent Mycobacterium tuberculosis infection. We studied the mutational rates of 24 index tuberculosis (TB) cases and their latently infected household contacts who developed active TB up to 5.25 years later, as an indication of bacterial physiological state an...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Colangeli, Roberto, Gupta, Aditi, Vinhas, Solange Alves, Chippada Venkata, Uma Deepthi, Kim, Soyeon, Grady, Courtney, Jones-López, Edward C., Soteropoulos, Patricia, Palaci, Moisés, Marques-Rodrigues, Patrícia, Salgame, Padmini, Ellner, Jerrold J., Dietze, Reynaldo, Alland, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519141/
https://ncbi.nlm.nih.gov/pubmed/32978384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18699-9
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