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Radiogenomic signatures reveal multiscale intratumour heterogeneity associated with biological functions and survival in breast cancer

Advanced tumours are often heterogeneous, consisting of subclones with various genetic alterations and functional roles. The precise molecular features that characterize the contributions of multiscale intratumour heterogeneity to malignant progression, metastasis, and poor survival are largely unkn...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Fan, Ming, Xia, Pingping, Clarke, Robert, Wang, Yue, Li, Lihua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519071/
https://ncbi.nlm.nih.gov/pubmed/32978398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18703-2
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