Application of pulsed laser ablation (PLA) for the size reduction of non-steroidal anti-inflammatory drugs (NSAIDs)

We studied the application of pulsed laser ablation (PLA) for particle size reduction in non-steroidal anti-inflammatory drugs (NSAIDs). Grinding of the poorly water-soluble NSAID crystallites can considerably increase their solubility and bioavailability, thereby the necessary doses can be reduced...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gera, Tamás, Nagy, Eszter, Smausz, Tamás, Budai, Judit, Ajtai, Tibor, Kun-Szabó, Fruzsina, Homik, Zsolt, Kopniczky, Judit, Bozóki, Zoltán, Szabó-Révész, Piroska, Ambrus, Rita, Hopp, Béla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519063/
https://ncbi.nlm.nih.gov/pubmed/32978489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72865-z
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