Part 1: profiling extra cellular matrix core proteome of human fetal nucleus pulposus in search for regenerative targets

Intervertebral disc degeneration is accompanied by a loss of Extra-cellular matrix (ECM) due to an imbalance in anabolic and catabolic pathways. Identifying ECM proteins with anabolic and/or regenerative potential could be the key to developing regenerative therapies. Since human fetal discs grow an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rajasekaran, Shanmuganathan, Tangavel, Chitraa, Djuric, Niek, Raveendran, Muthurajan, Soundararajan, Dilip Chand Raja, Nayagam, Sharon Miracle, Matchado, Monica Steffi, Anand, K. S. Sri Vijay
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519061/
https://ncbi.nlm.nih.gov/pubmed/32973250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72859-x
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