Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets

Control of the protein phosphorylation status is a major mechanism for regulation of cellular processes, and its alteration often lead to functional disorders. Ppz1, a protein phosphatase only found in fungi, is the most toxic protein when overexpressed in Saccharomyces cerevisiae. To investigate th...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Velázquez, Diego, Albacar, Marcel, Zhang, Chunyi, Calafí, Carlos, López-Malo, María, Torres-Torronteras, Javier, Martí, Ramón, Kovalchuk, Sergey I., Pinson, Benoit, Jensen, Ole N., Daignan-Fornier, Bertrand, Casamayor, Antonio, Ariño, Joaquín
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519054/
https://ncbi.nlm.nih.gov/pubmed/32973189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72391-y
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