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Effects of the autophagy modulators d-limonene and chloroquine on vimentin levels in SH-SY5Y cells

The molecular target and mechanism by which d-limonene induces LC3 lipidation and autophagosome formation remain elusive. Here, we report that this monoterpene rapidly enhances Ca(2+) levels in SH-SY5Y cells; yet this effect does not lead to calpain- or caspase-mediated proteolysis of α-spectrin, no...

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Bibliografiske detaljer
Udgivet i:Biochem Biophys Res Commun
Main Authors: Gentile, Debora, Berliocchi, Laura, Russo, Rossella, Bagetta, Giacinto, Corasaniti, Maria Tiziana
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518972/
https://ncbi.nlm.nih.gov/pubmed/32988589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.09.073
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