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Design of novel viral attachment inhibitors of the spike glycoprotein (S) of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) through virtual screening and dynamics

To date, the global COVID-19 pandemic has been associated with 11.8 million cases and over 545481 deaths. In this study, we have employed virtual screening approaches and selected 415 lead-like compounds from 103 million chemical substances, based on the existing drugs, from PubChem databases as pot...

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Detalhes bibliográficos
Publicado no:Int J Antimicrob Agents
Main Authors: Oany, Arafat Rahman, Mia, Mamun, Pervin, Tahmina, Junaid, Md., Hosen, S. M. Zahid, Moni, Mohammad Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd and International Society of Antimicrobial Chemotherapy. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518233/
https://ncbi.nlm.nih.gov/pubmed/32987103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2020.106177
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