Chemotherapy Controls Metastasis Through Stimulatory Effects on GRP78 and Its Transcription Factor CREB3L1

To achieve a cure for metastatic breast cancer, further understanding of molecular drivers of the metastatic cascade is essential. Currently, chemotherapy regimens include doxorubicin and paclitaxel which act in part by inducing the unfolded protein response (UPR). The master regulator of the UPR, g...

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Vydáno v:Front Oncol
Hlavní autoři: Raiter, Annat, Lipovetsky, Julia, Hyman, Lucila, Mugami, Shany, Ben-Zur, Tali, Yerushalmi, Rinat
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518037/
https://ncbi.nlm.nih.gov/pubmed/33042795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01500
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