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Aldehyde dehydrogenase 2 preserves mitochondrial morphology and attenuates hypoxia/reoxygenation-induced cardiomyocyte injury

BACKGROUND: Disturbance of mitochondrial fission and fusion (termed mitochondrial dynamics) is one of the leading causes of ischemia/reperfusion (I/R)-induced myocardial injury. Previous studies showed that mitochondrial aldehyde dehydrogenase 2 (ALDH2) conferred cardioprotective effect against myoc...

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Опубликовано в: :World J Emerg Med
Главные авторы: Zhang, Rui, Xue, Meng-yang, Liu, Bao-shan, Wang, Wen-jun, Fan, Xin-hui, Zheng, Bo-yuan, Yuan, Qiu-huan, Xu, Feng, Wang, Jia-li, Chen, Yu-guo
Формат: Artigo
Язык:Inglês
Опубликовано: Second Affiliated Hospital of Zhejiang University School of Medicine 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517403/
https://ncbi.nlm.nih.gov/pubmed/33014221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5847/wjem.j.1920-8642.2020.04.007
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