Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis

Galectin-3 (Gal-3) is an extracellular matrix glycan-binding protein with several immunosuppressive and pro-tumor functions. The role of Galectin-3 in cancer stem-like cells (CSCs) is poorly investigated. Here, we show that prostate CSCs also colonizing prostate-draining lymph nodes of transgenic ad...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Caputo, Sara, Grioni, Matteo, Brambillasca, Chiara S., Monno, Antonella, Brevi, Arianna, Freschi, Massimo, Piras, Ignazio S., Elia, Angela R., Pieri, Valentina, Baccega, Tania, Lombardo, Angelo, Galli, Rossella, Briganti, Alberto, Doglioni, Claudio, Jachetti, Elena, Bellone, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516304/
https://ncbi.nlm.nih.gov/pubmed/33013832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01820
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