Irisin Attenuates Myocardial Ischemia/Reperfusion Injury and Improves Mitochondrial Function Through AMPK Pathway in Diabetic Mice

AIMS: Several recent reports have shown irisin protects the heart against ischemia/reperfusion injury. However, the effect of irisin on I/R injury in diabetic mice has not been described. The present study was designed to investigate the role of irisin in myocardial ischemia-reperfusion (MI/R) injur...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xin, Chao, Zhang, Zheng, Gao, Guojie, Ding, Liping, Yang, Chao, Wang, Chengzhu, Liu, Yanjun, Guo, Yufei, Yang, Xueqing, Zhang, Lijuan, Zhang, Lina, Liu, Yi, Jin, Zhitao, Tao, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516196/
https://ncbi.nlm.nih.gov/pubmed/33013403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.565160
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