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Cerebral Fructose Metabolism as a Potential Mechanism Driving Alzheimer’s Disease

The loss of cognitive function in Alzheimer’s disease is pathologically linked with neurofibrillary tangles, amyloid deposition, and loss of neuronal communication. Cerebral insulin resistance and mitochondrial dysfunction have emerged as important contributors to pathogenesis supporting our hypothe...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Johnson, Richard J., Gomez-Pinilla, Fernando, Nagel, Maria, Nakagawa, Takahiko, Rodriguez-Iturbe, Bernardo, Sanchez-Lozada, Laura G., Tolan, Dean R., Lanaspa, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516162/
https://ncbi.nlm.nih.gov/pubmed/33024433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.560865
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