Discoidin Domain Receptors in Melanoma: Potential Therapeutic Targets to Overcome MAPK Inhibitor Resistance

Melanoma is a highly malignant skin cancer with high propensity to metastasize and develop drug resistance, making it a difficult cancer to treat. Current therapies targeting BRAF (V600) mutations are initially effective, but eventually tumors overcome drug sensitivity and reoccur. This process is a...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Reger de Moura, Coralie, Prunotto, Marco, Sohail, Anjum, Battistella, Maxime, Jouenne, Fanelie, Marbach, Daniel, Lebbé, Celeste, Fridman, Rafael, Mourah, Samia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516126/
https://ncbi.nlm.nih.gov/pubmed/33014862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01748
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