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The Genetic Mechanisms Driving Diversification of the KIR Gene Cluster in Primates

The activity and function of natural killer (NK) cells are modulated through the interactions of multiple receptor families, of which some recognize MHC class I molecules. The high level of MHC class I polymorphism requires their ligands either to interact with conserved epitopes, as is utilized by...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bruijnesteijn, Jesse, de Groot, Natasja G., Bontrop, Ronald E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516082/
https://ncbi.nlm.nih.gov/pubmed/33013938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.582804
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