Organoids to Study Intestinal Nutrient Transport, Drug Uptake and Metabolism – Update to the Human Model and Expansion of Applications

Intestinal transport and sensing processes and their interconnection to metabolism are relevant to pathologies such as malabsorption syndromes, inflammatory diseases, obesity and type 2 diabetes. Constituting a highly selective barrier, intestinal epithelial cells absorb, metabolize, and release nut...

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Veröffentlicht in:Front Bioeng Biotechnol
Hauptverfasser: Zietek, Tamara, Giesbertz, Pieter, Ewers, Maren, Reichart, Florian, Weinmüller, Michael, Urbauer, Elisabeth, Haller, Dirk, Demir, Ihsan Ekin, Ceyhan, Güralp O., Kessler, Horst, Rath, Eva
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Bioengineering and Biotechnology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7516017/
https://ncbi.nlm.nih.gov/pubmed/33015026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.577656
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