Abiraterone acetate preferentially enriches for the gut commensal Akkermansia muciniphila in castrate-resistant prostate cancer patients

Abiraterone acetate (AA) is an inhibitor of androgen biosynthesis, though this cannot fully explain its efficacy against androgen-independent prostate cancer. Here, we demonstrate that androgen deprivation therapy depletes androgen-utilizing Corynebacterium spp. in prostate cancer patients and that...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Daisley, Brendan A., Chanyi, Ryan M., Abdur-Rashid, Kamilah, Al, Kait F., Gibbons, Shaeley, Chmiel, John A., Wilcox, Hannah, Reid, Gregor, Anderson, Amanda, Dewar, Malcolm, Nair, Shiva M., Chin, Joseph, Burton, Jeremy P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515896/
https://ncbi.nlm.nih.gov/pubmed/32973149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18649-5
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