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Kir3 channel blockade in the cerebellar cortex suppresses performance of classically conditioned Purkinje cell responses

In the eyeblink conditioning paradigm, cerebellar Purkinje cells learn to respond to the conditional stimulus with an adaptively timed pause in its spontaneous firing. Evidence suggests that the pause is elicited by glutamate released from parallel fibers and acting on metabotropic receptors (mGluR7...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Johansson, Fredrik, Hesslow, Germund
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515874/
https://ncbi.nlm.nih.gov/pubmed/32973240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72581-8
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