A metabolic pathway for activation of dietary glucosinolates by a human gut symbiont

Consumption of glucosinolates, pro-drug like metabolites abundant in brassica vegetables, has been associated with decreased risk of certain cancers. Gut microbiota have the ability to metabolize glucosinolates, generating chemopreventive isothiocyanates. Here, we identify a genetic and biochemical...

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Gepubliceerd in:Cell
Hoofdauteurs: Liou, Catherine S., Sirk, Shannon J., Diaz, Camil A.C., Klein, Andrew P., Fischer, Curt R., Higginbottom, Steven K., Erez, Amir, Donia, Mohamed S., Sonnenburg, Justin L., Sattely, Elizabeth S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515767/
https://ncbi.nlm.nih.gov/pubmed/32084341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.01.023
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